Fundamentals of organic synthesisSyllabus

Subject code

İFS-3070y

Credits

7

Student workload

210

Semester

Autumn semester

Academic year

2025-2026

Subject type

Elective

Form of education

Full-time

Language of instruction

Azerbaijani

In-class hours

a) Mühazirə-45 saat b) Seminar- 15 saat

Out-of-class hours

a) TSİ- 90 saat MRTSİ-55 saat

The subject "fundamentals of organic synthesis" presents the general methodology, strategy and tactics of organic synthesis, retrosynthetic planning rules for the synthesis of mono- and polyfunctional compounds and their application in the example of the synthesis of medicinal, aromatic, food and taste compounds, plant protection agents, pheromones, dyes and flotomaterials.

• lecture
• seminar
• teamwork
• presentations

1. 1

   CLO 1: It explains the basic concepts, methodology, strategy and tactics of organic synthesis.

2. 2

   CLO 2: It applies the principles of retrosynthetic planning of mono- and polyfunctional organic compounds and develops synthesis routes.

3. 3

   CLO 3: Analyzes organic synthesis reactions according to the influence of reagents, catalysts and reaction conditions and chooses the optimal synthesis method.

4. 4

   CLO 4: Evaluates the synthesis processes of pharmaceuticals, flavorings, food and flavor compounds, plant protection agents, pheromones, dyes and fluororeagents and justifies their application areas.

5. 5

   CLO 5: Evaluating organic synthesis processes in terms of safety, productivity, economic efficiency and environmental protection, it offers suitable technological solutions.

6. 6

   CLO 6: Apply theoretical knowledge of organic synthesis to solve chemical engineering problems, analyze synthesis results and make scientifically based decisions.

1. 1.
   Introduction Lecture

   Introduction. ways of conducting organic synthesis.

2. 2.
   Creation and opening of cycles.Lecture

   Examples of intramolecular cyclization as a result of electrophilic-nucleophilic interaction. intramolecular cyclization, baldwin's rules. compounding on michael in cyclization processes.

3. 3.
   Formation of heterocyclic systemsLecture

   Formation of heterocyclic systems. cycloaddition reactions. electrocyclic cyclization. opening cycles.

4. 4.
   Application of element organic compounds in synthesisLecture

   Application of element organic compounds in synthesis. grignard reagent. examples of complete synthesis. new principles of stimulation of biological reactions

5. 5.
   Photochemical effectLecture

   Radiation chemistry. application of extreme high pressure. application of lasers. electrochemical synthesis. enzymatic catalysis in synthesis. use of metal-complex catalysis

6. 6.
   Synthesis of substances of practical value.Lecture

   Synthesis of substances of practical value. searching for practically valuable items.

7. 7.
   Fundamentals of civil defense. purpose, main events and tasks of civil defense. principles of the organization of civil defense in the republic of azerbaijan. civil defense forces. non-military formations of civil defense.Lecture
8. 8.
   Change of functional groups

   Change, insertion and interconversions of functional groups.

9. 9.
   Introduction of functional groups to hydrocarbons and heterocyclic compounds.

   Introduction of functional groups to hydrocarbons and heterocyclic compounds. addition of functional groups to alkanes and cycloalkanes.

10. 10.
    Addition of functional groups to alkenes

    Addition of functional groups to alkenes. addition of functional groups to alkynes. addition of functional groups to cycloolefins and cycloalkynes.

11. 11.
    Addition of functional groups to aromatic hydrocarbons.

    Addition of functional groups to aromatic hydrocarbons. hüvədə əvəzetmə. side chain reactions. introduction of functional groups to benzene derivatives.

12. 12.
    Insertion of functional groups into heterocyclic compounds

    Introduction of functional groups to simple heterocyclic compounds

13. 13.
    Interchanges of functional groups

    Interchanges of functional groups. transformations of the hydroxyl group. transformations of the amine group. transformations of halogen derivatives.

14. 14.
    Transformations of nitrocompounds.

    Transformations of nitrocompounds. transformations of aldehydes and ketones. transformations of organic acids and their derivatives.

15. 15.
    The principle of least change in the structure of the molecule.

    The principle of least change in the structure of the molecule. reactive sites in organic molecules. low energy communications.

16. 16.
    Polar and readily polarizable compounds.

    Polar and readily polarizable compounds. -connections. atoms with lone pairs of electrons.

17. 17.
    Methods of protection of functional groups.

    Methods of protection of functional groups. activation of functional groups. the influence of the nature of the solvent on the direction of the reaction. the main types of synthesis.

18. 18.
    Breaking down and assembling communications.

    Breaking down and assembling communications. possibility of using EHM in synthesis planning.

19. 19.
    We understand about synthons and synthetic equivalents.

    We understand about synthons and synthetic equivalents. using automatic devices in synthesis ("synthesizers"). interfacial catalysis in synthesis.

20. 20.
    Synthesis of substances of practical value.

    Synthesis of substances of practical value. searching for practically valuable items.

21. 21.
    Important aspects of elegant organic synthesis.Lecture

    Important aspects of elegant organic synthesis. biologically active compounds for medical needs. biologically active substances (pesticides) for agricultural needs. chemical reagents and dyes.

22. 22.
    Features such as fine organic synthesis field.Lecture

    Features such as fine organic synthesis field. multi-stage and complexity of the synthesis process.

23. 23.
    Features such as fine organic synthesis field. multi-stage and complexity of the synthesis process.Lecture

    Features such as fine organic synthesis field. multi-stage and complexity of the synthesis process.

24. 24.
    Creation and opening of cycles. examples of intramolecular cyclization as a result of electrophilic-nucleophilic interaction. intramolecular cyclization, baldwin's rules. compounding on michael in cyclization processes.Seminar

    Creation and opening of cycles. examples of intramolecular cyclization as a result of electrophilic-nucleophilic interaction. intramolecular cyclization, baldwin's rules. compounding on michael in cyclization processes.

25. 25.
    Formation of heterocyclic systems. cycloaddition reactions. electrocyclic cyclization. opening cyclesSeminar

    Formation of heterocyclic systems. cycloaddition reactions. electrocyclic cyclization. opening cycles

26. 26.
    Application of element organic compounds in synthesis. grignard reagent. examples of complete synthesis. new principles of stimulation of biological reactions.Seminar

    Formation of heterocyclic systems. cycloaddition reactions. electrocyclic cyclization. opening cycles

27. 27.
    Application of element organic compounds in synthesis. grignard reagent. examples of complete synthesis. new principles of stimulation of biological reactions.Seminar

    Formation of heterocyclic systems. cycloaddition reactions. electrocyclic cyclization. opening cycles

28. 28.
    Photochemical effect. radiation chemistry. application of extreme high pressure. application of lasers. electrochemical synthesis. enzymatic catalysis in synthesis. use of metal-complex catalysisSeminar

    Photochemical effect. radiation chemistry. i̇frat yüksək təzyiqin tətbi. application of lasers. electrochemical synthesis. enzymatic catalysis in synthesis. use of metal-complex catalysis

29. 29.
    Creation and opening of cycles.Seminar

    Creation and opening of cycles. examples of intramolecular cyclization as a result of electrophilic-nucleophilic interaction.

30. 30.
    Intramolecular cyclization, michael's coupling in processes.Seminar

    Intramolecular cyclization, michael's coupling in processes.

31. 31.
    Baldwin rules. cyclizationSeminar

    Baldwin rules. cyclization

32. 32.
    Openflow protokolu və flow table mexanizmiLecture

    Openflow protokolunun əsas prinsipləri, SDN kontrolleri ilə şəbəkə avadanlığı arasında əlaqə və flow table mexanizminin quruluşu öyrənilir.

33. 33.
    Electrocyclic cyclization. opening cycles.Seminar

    Electrocyclic cyclization. opening cycles.

34. 34.
    Synthesis planning. strategy and tactics of synthesis. schemes of synthesis. requirements for synthetic reactions.Independent work

    Synthesis planning. strategy and tactics of synthesis. schemes of synthesis. requirements for synthetic reactions.

35. 35.
    Breaking down and assembling communications. possibility of using EHM in synthesis planning.Independent work

    Breaking down and assembling communications. possibility of using EHM in synthesis planning.

36. 36.
    Understanding of synthons and synthetic equivalents. using automatic devices in synthesis ("synthesizers"). interfacial catalysis in synthesis.Independent work

    Understanding of synthons and synthetic equivalents. using automatic devices in synthesis ("synthesizers"). interfacial catalysis in synthesis.

37. 37.
    Creation and opening of cycles. examples of intramolecular cyclization as a result of electrophilic-nucleophilic interaction. intramolecular cyclization, baldwin's rules. compounding on michael in cyclization processes.Independent work

    Creation and opening of cycles. examples of intramolecular cyclization as a result of electrophilic-nucleophilic interaction. intramolecular cyclization, baldwin's rules. compounding on michael in cyclization processes.

38. 38.
    Formation of heterocyclic systems. cycloaddition reactions. electrocyclic cyclization. opening cycles.Independent work

    Formation of heterocyclic systems. cycloaddition reactions. electrocyclic cyclization. opening cycles.

39. 39.
    Application of element organic compounds in synthesis. grignard reagent. examples of complete synthesis. new principles of stimulation of organic reactions.Independent work

    Application of element organic compounds in synthesis. grignard reagent. examples of complete synthesis. new principles of stimulation of biological reactions.

40. 40.
    Photochemical effect. radiation chemistry. application of extremely high pressure. application of lasers. electrochemical synthesis. enzymatic catalysis in synthesis. use of metal-complex catalysisIndependent work

    Photochemical effect. radiation chemistry. application of extremely high pressure. application of lasers. electrochemical synthesis. enzymatic catalysis in synthesis. use of metal-complex catalysis

41. 41.
    Synthesis of substances of practical value. searching for practically valuable items.Independent work

    Synthesis of substances of practical value. searching for practically valuable items.

42. 42.
    Myhym directions for elegant writing. biologically active compounds for medical needs. biologically active substances (pesticides) for agricultural needs. chemical reagents and paintIndependent work

    Myhym directions for elegant writing. biologically active compounds for medical needs. biologically active substances (pesticides) for agricultural needs. chemical reagents and paint

43. 43.
    Characteristics of fine organic synthesis as a field of study. multi-stage and complexity of the synthesis process.Independent work

    Characteristics of fine organic synthesis as a field of study. multi-stage and complexity of the synthesis process.

No reading list has been added.